Chondrosarcoma is a malignant cancer that results in abnormal bone and/or cartilage growth. People who have chondrosarcoma have a tumor growth, or abnormal bony type of bump, which can vary in size and location. The term chondrosarcoma is used to define a heterogeneous group of lesions with diverse features and clinical behavior. Primary chondrosarcoma (or conventional chondrosarcoma) usually develops centrally in a previously normal bone. Secondary chondrosarcoma is a chondrosarcoma arising from a benign precursor such as enchondromas or osteochondromas. Chondrosarcoma is the second most common primary bone cancer. The malignant cartilage cells begin growing within or on the bone (central chondrosarcoma) or, rarely, secondarily within the cartilaginous cap of a pre-existing osteochondroma (peripheral chondrosarcoma). There are several different types of chondrosarcoma, with names based on the type of cells identified when they are examined under a microscope (see next section for detailed descriptions). Dr. R. Lor Randall and  Dr. Kenneth J. Hunt of the Huntsman Cancer Institute & Primary Children’s Medical Center have have written an in-depth article, Chondrosarcoma of Bone, for our Electronic Sarcoma Update Newsletter (ESUN). Their article gives an extensive set of references to articles dealing with this disease. We are grateful to them, both of who are extremely busy physicians and researchers, for finding the time to undertake this project. Click on the above link to view their article.